The efficacy of polyphenols can be influenced by variables such as the composition of the diet, the process of digestion, and variations in individual metabolism, which complicates the establishment of uniform treatment (Martemucci et al., 2024)
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This review evaluates the current evidence on combination therapies involving SGLT2is, GLP-1RAs, and nsMRAs in type 1 and type 2 diabetes, thereby focusing on treatments that in type 2 diabetes have shown cardio-renal protection, while exploring future research directions
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